Pharmacogenetics

 
To optimise efficacy and avoid adverse effects, pharmacotherapy must be tailored to the individual patient. The ideal dosage depends on genetic (inherited), individual and environmental factors. Genetic factors determine the activity of drug-degrading enzymes and drug transporters (pharmacokinetics) and the receptors on which drugs act (pharmacodynamics). Many genetic factors relevant to drug dosing can be analysed and quantified (genotyping).

As the relevant genes (and mutations) are inherited and therefore remain constant throughout life, they only need to be analysed once in a person's lifetime.

Medisyn offers the analysis of single genes as well as whole gene panels and provides interpretation of the results. For further questions, Medisyn offers detailed clinical-pharmacological advice.